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Details on Person PKC phosphorylates Nrf2

Class:IdReaction:8932373
_displayNamePKC phosphorylates Nrf2
_doReleaseTRUE
_timestamp2021-03-01 06:20:32
authored[InstanceEdit:8932363] Garapati, Phani Vijay, 2016-07-22
catalystActivity[CatalystActivity:8932364] diacylglycerol-dependent, calcium-independent serine/threonine kinase activity of Prkcd [cytosol]
catalystActivityReference[CatalystActivityReference:9643956] protein kinase C activity of Prkcd [cytosol] Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription
compartment[Compartment:70101] cytosol
created[InstanceEdit:8932363] Garapati, Phani Vijay, 2016-07-22
edited[InstanceEdit:9716626] Stephan, Ralf, 2021-02-23
input[EntityWithAccessionedSequence:8932326] Nfe2l2 [cytosol] [Rattus norvegicus]
[SimpleEntity:113592] ATP [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:8932342] Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription
modified[InstanceEdit:8932989] Wu, G, 2016-08-01
[InstanceEdit:8932990] Wu, G, 2016-08-01
[InstanceEdit:8932991] Wu, G, 2016-08-01
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9708449] Stephan, Ralf, 2020-11-30
[InstanceEdit:9713665] Stephan, Ralf, 2021-01-29
[InstanceEdit:9716626] Stephan, Ralf, 2021-02-23
[InstanceEdit:9716814] D'Eustachio, Peter, 2021-02-25
[InstanceEdit:9716828] Matthews, Lisa, 2021-03-01
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePKC phosphorylates Nrf2
output[EntityWithAccessionedSequence:8932345] p-S40-Nfe2l2 [cytosol] [Rattus norvegicus]
[SimpleEntity:29370] ADP [cytosol]
regulatedBy[PositiveRegulation:9665172] Positive regulation by 'ROS [cytosol]'
regulationReference[RegulationReference:9708561] Positive regulation by 'ROS [cytosol]' Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription
releaseDate2021-03-23
reviewed[InstanceEdit:9713327] Somers, Julia, 2021-01-23
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48895] Rattus norvegicus
stableIdentifier[StableIdentifier:8932389] R-RNO-8932373.2
summation[Summation:8932357] In response to oxidative stress, protein kinase C (PKC) phos...
(inferredFrom)[Reaction:8932284] PKC phosphorylates NFE2L2 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9775163] Update Tracker - [Reaction:8932373] PKC phosphorylates Nrf2 - v80:[modifyText]
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