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Details on Person The KEAP1:CUL3:RBX1 E3-ubiquitin ligase complex is a negativ...
| Class:Id | Summation:8932313 |
|---|---|
| _displayName | The KEAP1:CUL3:RBX1 E3-ubiquitin ligase complex is a negativ... |
| _timestamp | 2022-02-17 21:25:40 |
| created | [InstanceEdit:8932363] Garapati, Phani Vijay, 2016-07-22 |
| modified | [InstanceEdit:9708449] Stephan, Ralf, 2020-11-30 [InstanceEdit:9708956] Stephan, Ralf, 2020-12-04 [InstanceEdit:9755468] Rothfels, Karen, 2021-10-08 [InstanceEdit:9762212] Rothfels, Karen, 2022-01-18 [InstanceEdit:9766141] Rothfels, Karen, 2022-02-17 |
| text | The KEAP1:CUL3:RBX1 E3-ubiquitin ligase complex is a negative regulator of Nuclear factor erythroid 2-related (NFE2L2). In the absence of oxidative alterations this E3-ubiquitin ligase complex is bound to NFE2L2 and targets it for ubiquitination (Cullinan et al, 2004; Kobayashi et al, 2004; reviewed in Baird and Yamamoto, 2020). |
| (summation) | [Reaction:9755505] KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 [Homo sapiens] |
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No pathways have been reviewed or authored by The KEAP1:CUL3:RBX1 E3-ubiquitin ligase complex is a negativ... (8932313)
