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Query author contributions in Reactome

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Details on Person UniProt:Q9V4M2 wech

Class:IdReferenceGeneProduct:89323
_chainChangeLogchain:1-832 added on Sat February 7 2015
_displayNameUniProt:Q9V4M2 wech
_timestamp2025-08-15 21:35:23
chainchain:1-832
checksumA5672AFC3FDE1FE1
commentFUNCTION Vital for larval development. Plays a role in tumor formation. A crucial component for the physical link between integrins and the cytoskeleton in the epidermal muscle attachment sites.SUBUNIT Interacts with the head domain of rhea and the kinase domain of Ilk. Interacts with AGO1 (PubMed:18528333). Interacts with mei-P26 (PubMed:22438571).TISSUE SPECIFICITY Expressed in ovarian germline stem cells (at protein level) (PubMed:22438571). Expressed ubiquitously in all epithelial cells during early stages of embryogenesis. Specifically expressed at epidermal muscle attachment site.DEVELOPMENTAL STAGE Expressed both maternally and zygotically throughout development.DISRUPTION PHENOTYPE Muscle detachment in late-stage-16/early-stage-17 embryos.MISCELLANEOUS 'Wech' means 'detached' or 'gone' in German.CAUTION Was originally termed dappled.
descriptionrecommendedName: Protein wech alternativeName: Protein dappled
geneNamewech
dpld
CG42396
identifierQ9V4M2
isSequenceChangedFALSE
keywordDevelopmental protein
Differentiation
Metal-binding
Myogenesis
Phosphoprotein
Reference proteome
Repeat
Zinc
Zinc-finger
modified[InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
[InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12
[InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39
[InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18
[InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35
[InstanceEdit:423310] Kanapin, AA
[InstanceEdit:435478] Kanapin, AA
[InstanceEdit:435871] Kanapin, AA
[InstanceEdit:447347] Kanapin, AA
[InstanceEdit:525883] Kanapin, AA
[InstanceEdit:613449] Kanapin, AA
[InstanceEdit:797602] Kanapin, AA
[InstanceEdit:937368] Yung, CK
[InstanceEdit:1042053] Yung, CK
[InstanceEdit:1220657] Yung, CK
[InstanceEdit:1300696] Yung, CK
[InstanceEdit:1301627] Yung, CK
[InstanceEdit:1551960] Weiser, JD
[InstanceEdit:1995863] Weiser, JD
[InstanceEdit:2132304] Weiser, JD
[InstanceEdit:2265580] Weiser, JD
[InstanceEdit:5433710] Weiser, JD
[InstanceEdit:5618415] Weiser, JD
[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9963647] Weiser, Joel, 2025-08-15
namewech
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierWECH_DROME
A4IJ45
B7YZS8
Q0E9G5
Q95SY8
sequenceLength832
species[Species:56210] Drosophila melanogaster
(referenceEntity)[EntityWithAccessionedSequence:392371] WECH [cytosol] [Drosophila melanogaster]
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No pathways have been reviewed or authored by UniProt:Q9V4M2 wech (89323)