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Details on Person Expression of HIGD1A

Class:Id	BlackBoxEvent:8932184
_displayName	Expression of HIGD1A
_doRelease	TRUE
_timestamp	2016-08-09 01:07:21
authored	[InstanceEdit:8932159] May, Bruce, 2016-07-21
compartment	[Compartment:7660] nucleoplasm [Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:8932160] May, Bruce, 2016-07-21
edited	[InstanceEdit:8932159] May, Bruce, 2016-07-21
input	[EntityWithAccessionedSequence:8932190] HIGD1A gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8932185] HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth
modified	[InstanceEdit:8932989] Wu, G, 2016-08-01 [InstanceEdit:8932990] Wu, G, 2016-08-01 [InstanceEdit:8932991] Wu, G, 2016-08-01 [InstanceEdit:8934405] May, Bruce, 2016-08-09 [InstanceEdit:8934409] May, Bruce, 2016-08-09 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9733355] Wu, Guanming, 2021-06-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of HIGD1A
output	[EntityWithAccessionedSequence:8932180] HIGD1A [mitochondrial inner membrane] [Homo sapiens]
precedingEvent	[Reaction:1234171] HIF-alpha binds ARNT (HIF1-beta) forming HIF-alpha:ARNT [Homo sapiens] [BlackBoxEvent:1234161] HIF-alpha translocates from cytosol to nucleus [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:8932158] Positive gene expression regulation by 'HIF [nucleoplasm]'
regulationReference	[RegulationReference:9642423] Positive gene expression regulation by 'HIF [nucleoplasm]' HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth
releaseDate	2016-09-19
reviewed	[InstanceEdit:8934403] Maltepe, Emin, 2016-08-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8932195] R-HSA-8932184.5
summation	[Summation:8932167] The HIGD1A (RCF1A, HIG1) gene is transcribed to yield mRNA a... [Summation:8932174] HIF binds the promoter of the HIGD1A gene and activates tran...
(hasEvent)	[Pathway:1234158] Regulation of gene expression by Hypoxia-inducible Factor [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9775658] Update Tracker - [BlackBoxEvent:8932184] Expression of HIGD1A - v78:[addSummation]
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No pathways have been reviewed or authored by Expression of HIGD1A (8932184)