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Details on Person Synthesis of GABA by GAD2

Class:IdReaction:888577
_displayNameSynthesis of GABA by GAD2
_doReleaseTRUE
_timestamp2019-04-17 20:05:28
authored[InstanceEdit:888594] Mahajan, SS, 2010-06-29
catalystActivity[CatalystActivity:888587] glutamate decarboxylase activity of PXLP-GAD dimers [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
compartment[Compartment:917757] clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
[Compartment:917758] clathrin-sculpted gamma-aminobutyric acid transport vesicle
created[InstanceEdit:888571] Mahajan, SS, 2010-06-29
edited[InstanceEdit:918281] Mahajan, SS, 2010-08-03
input[SimpleEntity:29404] L-Glu [cytosol]
[SimpleEntity:70106] H+ [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:888576] GAD2 on chromosome 10p12 is a candidate gene for human obesity
modified[InstanceEdit:888600] Mahajan, SS, 2010-06-29
[InstanceEdit:918009] Mahajan, SS, 2010-07-30
[InstanceEdit:918258] Mahajan, SS, 2010-08-03
[InstanceEdit:936518] Mahajan, SS, 2010-08-23
[InstanceEdit:937313] Mahajan, SS, 2010-08-26
[InstanceEdit:9644714] D'Eustachio, Peter, 2019-04-17
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSynthesis of GABA by GAD2
output[SimpleEntity:352011] GABA [cytosol]
[SimpleEntity:113528] CO2 [cytosol]
releaseDate2010-09-21
reviewed[InstanceEdit:386898] Restituito, S, 2008-11-27 12:38:49
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1105422] R-HSA-888577.3
summation[Summation:888578] GAD65 or GAD2 is concentrated in the nerve terminal region i...
(hasEvent)[Pathway:888568] GABA synthesis [Homo sapiens]
(precedingEvent)[Reaction:888592] Loading of GABA into clathrin sculpted GABA transport vesicle lumen [Homo sapiens]
(updatedInstance)[_UpdateTracker:9777762] Update Tracker - [Reaction:888577] Synthesis of GABA by GAD2 - v69:[removeInput, removeOutput]
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