Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person JAG1 gene expression is inhibited by RUNX3

Class:Id	BlackBoxEvent:8878212
_displayName	JAG1 gene expression is inhibited by RUNX3
_doRelease	TRUE
_timestamp	2017-01-31 16:55:44
authored	[InstanceEdit:8951943] Orlic-Milacic, Marija, 2016-12-12
compartment	[Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created	[InstanceEdit:8878213] Orlic-Milacic, Marija, 2016-06-30
edited	[InstanceEdit:8959863] Orlic-Milacic, Marija, 2017-01-31
input	[EntityWithAccessionedSequence:8878209] JAG1 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8878203] Restored expression of the tumor suppressor gene RUNX3 reduces cancer stem cells in hepatocellular carcinoma by suppressing Jagged1-Notch signaling
modified	[InstanceEdit:8878219] Orlic-Milacic, Marija, 2016-06-30 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8941597] Orlic-Milacic, Marija, 2016-10-04 [InstanceEdit:8942333] Orlic-Milacic, Marija, 2016-10-12 [InstanceEdit:8959866] Orlic-Milacic, Marija, 2017-01-31 [InstanceEdit:8959882] Orlic-Milacic, Marija, 2017-01-31 [InstanceEdit:8959887] Orlic-Milacic, Marija, 2017-01-31 [InstanceEdit:8959889] Orlic-Milacic, Marija, 2017-01-31 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	JAG1 gene expression is inhibited by RUNX3
output	[EntityWithAccessionedSequence:157098] JAG1 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:8878193] RUNX3 binds the JAG1 gene promoter [Homo sapiens] [Reaction:8937814] RUNX3 translocates to the nucleus [Homo sapiens]
regulatedBy	[NegativeGeneExpressionRegulation:8878211] Negative gene expression regulation by 'RUNX3:JAG1 gene [nucleoplasm]'
regulationReference	[RegulationReference:9641412] Negative gene expression regulation by 'RUNX3:JAG1 gene [nucleoplasm]' Restored expression of the tumor suppressor gene RUNX3 reduces cancer stem cells in hepatocellular carcinoma by suppressing Jagged1-Notch signaling
releaseDate	2017-03-27
reviewed	[InstanceEdit:8959885] Ito, Yoshiaki, 2017-01-31 [InstanceEdit:8959883] Chuang, Linda Shyue Huey, 2017-01-31
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8922255] R-HSA-8878212.4
summation	[Summation:8878216] Binding of RUNX3 to the JAG1 gene promoter inhibits transcri...
(hasEvent)	[Pathway:8941856] RUNX3 regulates NOTCH signaling [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by JAG1 gene expression is inhibited by RUNX3 (8878212)