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Details on Person RUNX3 binds SMAD3 and SMAD4

Class:IdReaction:8878143
_displayNameRUNX3 binds SMAD3 and SMAD4
_doReleaseTRUE
_timestamp2017-11-24 18:51:05
authored[InstanceEdit:8951943] Orlic-Milacic, Marija, 2016-12-12
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:8878140] Orlic-Milacic, Marija, 2016-06-30
edited[InstanceEdit:8959863] Orlic-Milacic, Marija, 2017-01-31
input[EntityWithAccessionedSequence:8865393] RUNX3 [nucleoplasm] [Homo sapiens]
[Complex:8878153] p-2S-SMAD3:p-2S-SMAD3:SMAD4 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:8878139] RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD
[LiteratureReference:8959856] Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter
modified[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8959861] Orlic-Milacic, Marija, 2017-01-31
[InstanceEdit:8959882] Orlic-Milacic, Marija, 2017-01-31
[InstanceEdit:8959887] Orlic-Milacic, Marija, 2017-01-31
[InstanceEdit:8959889] Orlic-Milacic, Marija, 2017-01-31
[InstanceEdit:9029999] Orlic-Milacic, Marija, 2017-11-24
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameRUNX3 binds SMAD3 and SMAD4
output[Complex:8878146] RUNX3:p-2S-SMAD3:p-2S-SMAD3:SMAD4 [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2017-03-27
reviewed[InstanceEdit:8959885] Ito, Yoshiaki, 2017-01-31
[InstanceEdit:8959883] Chuang, Linda Shyue Huey, 2017-01-31
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8910293] R-HSA-8878143.3
summation[Summation:8878151] RUNX3 binds the complex of SMAD3 and SMAD4, formed in respon...
(hasEvent)[Pathway:8941855] RUNX3 regulates CDKN1A transcription [Homo sapiens]
(precedingEvent)[Reaction:8878178] The complex of RUNX3, SMAD3 and SMAD4 binds the CDKN1A gene promoter [Homo sapiens]
[Reaction:8952226] RUNX3 binds the BCL2L11 (BIM) gene [Homo sapiens]
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No pathways have been reviewed or authored by RUNX3 binds SMAD3 and SMAD4 (8878143)