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Details on Person FOXP3 in complex with RUNX1 binds to the TNFRSF18 (GITR) gene intron 1

Class:Id	Reaction:8877490
_displayName	FOXP3 in complex with RUNX1 binds to the TNFRSF18 (GITR) gene intron 1
_doRelease	TRUE
_timestamp	2017-05-09 14:03:51
authored	[InstanceEdit:8938982] Orlic-Milacic, Marija, 2016-09-14
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8877488] Orlic-Milacic, Marija, 2016-06-22
edited	[InstanceEdit:9005626] Orlic-Milacic, Marija, 2017-05-09
input	[Complex:8877193] RUNX1:CBFB:FOXP3 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8877484] TNFRSF18 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8877190] Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1 [LiteratureReference:8877864] FOXP3 controls regulatory T cell function through cooperation with NFAT
modified	[InstanceEdit:8877866] Orlic-Milacic, Marija, 2016-06-28 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9005630] Orlic-Milacic, Marija, 2017-05-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	FOXP3 in complex with RUNX1 binds to the TNFRSF18 (GITR) gene intron 1
output	[Complex:8877491] RUNX1:CBFB:FOXP3:TNFRSF18 gene [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:8877192] RUNX1 binds FOXP3 [Homo sapiens] [BlackBoxEvent:8865546] FOXP3 gene expression is stimulated by RUNX1:CBFB [Homo sapiens]
releaseDate	2017-06-12
reviewed	[InstanceEdit:9005627] Ito, Yoshiaki, 2016-12-20 [InstanceEdit:9005628] Chuang, Linda Shyue Huey, 2016-12-20
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8917648] R-HSA-8877490.2
summation	[Summation:8877489] FOXP3 bound to the RUNX1:CBFB complex binds to the first int...
(hasEvent)	[Pathway:8877330] RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:8877493] TNFRSF18 (GITR) gene expression is stimulated by FOXP3 and inhibited by RUNX1 [Homo sapiens]
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No pathways have been reviewed or authored by FOXP3 in complex with RUNX1 binds to the TNFRSF18 (GITR) gene intron 1 (8877490)