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Details on Person InlA:CDH1:CTNNB1:CTNND1 [plasma membrane]

Class:Id	Complex:8876504
_displayName	InlA:CDH1:CTNNB1:CTNND1 [plasma membrane]
_timestamp	2016-11-15 19:34:04
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:8876503] Orlic-Milacic, Marija, 2016-06-15
disease	[Disease:8875363] listeriosis
entityOnOtherCell	[EntityWithAccessionedSequence:8876505] InlA [Gram-positive-bacterium-type cell wall] [Listeria monocytogenes]
hasComponent	[EntityWithAccessionedSequence:8876505] InlA [Gram-positive-bacterium-type cell wall] [Listeria monocytogenes] [Complex:8877851] CDH1:CTNNB1:CTNND1 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:448839] CTNNB1 [cytosol] [Homo sapiens] [Complex:2534182] CDH1(155-882):Ca2+ dimer [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:198003] CDH1(155-882) [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:198003] CDH1(155-882) [plasma membrane] [Homo sapiens] [SimpleEntity:74112] Ca2+ [extracellular region] [SimpleEntity:74112] Ca2+ [extracellular region] [SimpleEntity:74112] Ca2+ [extracellular region] [SimpleEntity:74112] Ca2+ [extracellular region] [SimpleEntity:74112] Ca2+ [extracellular region] [SimpleEntity:74112] Ca2+ [extracellular region] [SimpleEntity:74112] Ca2+ [extracellular region] [SimpleEntity:74112] Ca2+ [extracellular region] [SimpleEntity:74112] Ca2+ [extracellular region] [SimpleEntity:74112] Ca2+ [extracellular region] [EntityWithAccessionedSequence:418996] CTNND1 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8876496] E-cadherin is the receptor for internalin, a surface protein required for entry of L. monocytogenes into epithelial cells
modified	[InstanceEdit:8876907] Orlic-Milacic, Marija, 2016-06-17 [InstanceEdit:8877852] Orlic-Milacic, Marija, 2016-06-28 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8935681] Weiser, JD [InstanceEdit:8943849] Orlic-Milacic, Marija, 2016-10-31 [InstanceEdit:8945689] Weiser, JD [InstanceEdit:8948213] Orlic-Milacic, Marija, 2016-11-11 [InstanceEdit:8948698] Orlic-Milacic, Marija, 2016-11-15 [InstanceEdit:8959586] Weiser, JD
name	InlA:CDH1:CTNNB1:CTNND1 Internalin A:E-cadherin:beta-catenin:p120 catenin
relatedSpecies	[Species:8875362] Listeria monocytogenes
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8916163] R-HSA-8876504.2
(input)	[BlackBoxEvent:8876948] SRC phosphorylates InlA-bound CDH1 and CTNNB1 [Homo sapiens]
(output)	[Reaction:8876497] InlA binds CDH1 [Homo sapiens]
(regulator)	[PositiveRegulation:8876920] Positive regulation by 'InlA:CDH1:CTNNB1:CTNND1 [plasma membrane]'
(updatedInstance)	[_UpdateTracker:9896590] Update Tracker - [Complex:8876504] InlA:CDH1:CTNNB1:CTNND1 [plasma membrane] - v60:[removeSpecies]
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No pathways have been reviewed or authored by InlA:CDH1:CTNNB1:CTNND1 [plasma membrane] (8876504)