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Details on Person CHOL translocates from lysosome membrane to ER membrane

Class:IdBlackBoxEvent:8876485
_displayNameCHOL translocates from lysosome membrane to ER membrane
_doReleaseTRUE
_timestamp2016-10-19 09:15:21
authored[InstanceEdit:8876477] Jassal, Bijay, 2016-06-15
compartment[Compartment:12045] endoplasmic reticulum membrane
[Compartment:17938] lysosomal membrane
created[InstanceEdit:8876477] Jassal, Bijay, 2016-06-15
edited[InstanceEdit:8876477] Jassal, Bijay, 2016-06-15
input[Complex:8876475] NPC1:CHOL [lysosomal membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:8876462] NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes
[LiteratureReference:8876360] Lysosomal acid lipase: at the crossroads of normal and atherogenic cholesterol metabolism
modified[InstanceEdit:8876698] Jassal, Bijay, 2016-06-16
[InstanceEdit:8876748] Jassal, Bijay, 2016-06-16
[InstanceEdit:8878922] Jassal, Bijay, 2016-07-14
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8942661] Jassal, Bijay, 2016-10-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCHOL translocates from lysosome membrane to ER membrane
output[SimpleEntity:193384] CHOL [endoplasmic reticulum membrane]
[EntityWithAccessionedSequence:5216153] NPC1 [lysosomal membrane] [Homo sapiens]
precedingEvent
releaseDate2016-12-12
reviewed[InstanceEdit:8942662] D'Eustachio, Peter, 2016-10-19
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8915947] R-HSA-8876485.2
summation[Summation:8876465] In macrophages, the hydrolysis of cholesteryl esters (CHESTs...
(hasEvent)[Pathway:8964038] LDL clearance [Homo sapiens]
(precedingEvent)[Reaction:8876696] SOAT1,2 transfer acyl group to CHOL forming CHEST [Homo sapiens]
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No pathways have been reviewed or authored by CHOL translocates from lysosome membrane to ER membrane (8876485)