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Details on Person NPC1L1 transports CHOL from extracellular region to cytosol

Class:Id	Reaction:8876473
_displayName	NPC1L1 transports CHOL from extracellular region to cytosol
_doRelease	FALSE
_timestamp	2016-10-28 08:11:18
catalystActivity	[CatalystActivity:8876482] cholesterol transfer activity of NPC1L1 [plasma membrane]
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:8876477] Jassal, Bijay, 2016-06-15
input	[SimpleEntity:171149] CHOL [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:8876483] Novel function of Niemann-Pick C1-like 1 as a negative regulator of Niemann-Pick C2 protein [LiteratureReference:265538] The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)
modified	[InstanceEdit:8879142] Jassal, Bijay, 2016-07-15 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8932134] Jassal, Bijay, 2016-07-21 [InstanceEdit:8943659] Jassal, Bijay, 2016-10-28
name	NPC1L1 transports CHOL from extracellular region to cytosol
output	[SimpleEntity:176478] CHOL [cytosol]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8929643] R-HSA-8876473.1
summation	[Summation:8876486] Niemann-Pick C1-like protein 1 (NCP1L1) is a critical mediat...
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No pathways have been reviewed or authored by NPC1L1 transports CHOL from extracellular region to cytosol (8876473)