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Details on Person CIN85 is necessary for endocytosis-mediated entry of Listeri...
| Class:Id | Summation:8876250 |
|---|---|
| _displayName | CIN85 is necessary for endocytosis-mediated entry of Listeri... |
| _timestamp | 2016-06-20 14:37:52 |
| created | [InstanceEdit:8876252] Orlic-Milacic, Marija, 2016-06-10 |
| literatureReference | [LiteratureReference:8875355] Listeria hijacks the clathrin-dependent endocytic machinery to invade mammalian cells [LiteratureReference:8875449] The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met |
| modified | [InstanceEdit:8877128] Orlic-Milacic, Marija, 2016-06-20 |
| text | CIN85 is necessary for endocytosis-mediated entry of Listeria monocytogenes triggered by CBL-mediated monoubiquitination of MET receptor activated by binding to the bacterial cell wall protein InlB (Veiga et al. 2005). Based on the analogy with HGF-activated MET signaling (Petrelli et al. 2002), CBL recruits the complex of CIN85 and endophilin to Listeria-engaged MET. |
| (summation) | [Reaction:8876255] CBL recruits CIN85:endophilin complex to InlB-bound MET [Homo sapiens] |
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No pathways have been reviewed or authored by CIN85 is necessary for endocytosis-mediated entry of Listeri... (8876250)
