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Details on Person Binding of InlB to MET receptor induces CBL phosphorylation ...
| Class:Id | Summation:8876244 |
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| _displayName | Binding of InlB to MET receptor induces CBL phosphorylation ... |
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| _timestamp | 2016-06-28 14:39:08 |
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| created | [InstanceEdit:8876248] Orlic-Milacic, Marija, 2016-06-10 |
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| literatureReference | [LiteratureReference:8875449] The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met
[LiteratureReference:8874693] Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein |
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| modified | [InstanceEdit:8876381] Orlic-Milacic, Marija, 2016-06-14
[InstanceEdit:8877127] Orlic-Milacic, Marija, 2016-06-20
[InstanceEdit:8877849] Orlic-Milacic, Marija, 2016-06-28 |
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| text | Binding of InlB to MET receptor induces CBL phosphorylation on tyrosine residue(s). Based on the analogy with HGF-induced MET signaling, MET receptor activated by binding of the Listeria monocytogenes protein InlB phosphorylates CBL, promoting stronger interaction of CBL with MET (Peschard et al. 2001, Petrelli et al. 2002). |
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| (summation) | [Reaction:8876246] InlB-activated MET phosphorylates CBL [Homo sapiens] |
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