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Details on Person RAB9 GEFs exchange GTP for GDP on RAB9

Class:Id	Reaction:8876191
_displayName	RAB9 GEFs exchange GTP for GDP on RAB9
_doRelease	TRUE
_timestamp	2017-05-26 15:29:37
authored	[InstanceEdit:8878001] Rothfels, Karen, 2016-06-28
catalystActivity	[CatalystActivity:8876176] guanyl-nucleotide exchange factor activity of RAB9 GEFs [cytosol]
compartment	[Compartment:263163] trans-Golgi network membrane [Compartment:70101] cytosol
created	[InstanceEdit:8876192] Rothfels, Karen, 2016-06-09
edited	[InstanceEdit:8878001] Rothfels, Karen, 2016-06-28
input	[SimpleEntity:29438] GTP [cytosol] [Complex:8876113] GGC-RAB9:GDP:GDIs,CHMs [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:6811214] Dual roles of the mammalian GARP complex in tethering and SNARE complex assembly at the trans-golgi network [LiteratureReference:6811243] Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes [LiteratureReference:6814595] TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking [LiteratureReference:6814583] RhoBTB3: a Rho GTPase-family ATPase required for endosome to Golgi transport [LiteratureReference:6811218] Entry at the trans-face of the Golgi [LiteratureReference:6814845] Membrane tethering [LiteratureReference:2457791] Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors [LiteratureReference:8877734] Multiple Types of Guanine Nucleotide Exchange Factors (GEFs) for Rab Small GTPases [LiteratureReference:8871106] Rab proteins and the compartmentalization of the endosomal system
modified	[InstanceEdit:8876855] Rothfels, Karen, 2016-06-16 [InstanceEdit:8878001] Rothfels, Karen, 2016-06-28 [InstanceEdit:8878004] Rothfels, Karen, 2016-06-28 [InstanceEdit:8878060] Rothfels, Karen, 2016-06-29 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8933463] Rothfels, Karen, 2016-08-04 [InstanceEdit:9007100] Jupe, Steve, 2017-05-26 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RAB9 GEFs exchange GTP for GDP on RAB9
output	[SimpleEntity:29420] GDP [cytosol] [DefinedSet:8875305] GDIs,CHMs [cytosol] [Homo sapiens] [Complex:8876110] GGC-RAB9:GTP [trans-Golgi network membrane] [Homo sapiens]
releaseDate	2016-09-19
reviewed	[InstanceEdit:8933218] Marat, Andrea L, 2016-08-03
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8915590] R-HSA-8876191.3
summation	[Summation:8876182] RAB9 plays a role in the retrograde traffic of cargo such as...
(hasEvent)	[Pathway:8876198] RAB GEFs exchange GTP for GDP on RABs [Homo sapiens]
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