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Details on Person MET binds and phosphorylates the adapter protein GAB1, thus ...
| Class:Id | Summation:8875933 |
|---|---|
| _displayName | MET binds and phosphorylates the adapter protein GAB1, thus ... |
| _timestamp | 2016-06-13 17:24:57 |
| created | [InstanceEdit:8875932] Orlic-Milacic, Marija, 2016-06-09 |
| modified | [InstanceEdit:8876059] Orlic-Milacic, Marija, 2016-06-09 [InstanceEdit:8876343] Orlic-Milacic, Marija, 2016-06-13 |
| text | MET binds and phosphorylates the adapter protein GAB1, thus creating a docking site for the regulatory subunit PIK3R1 of the PI3K complex. Recruitment of PI3K to MET-bound phosphorylated GAB1 results in PI3K activation, production of PIP3, and stimulation of downstream AKT signaling (Rodrigues et al. 2000, Schaeper et al. 2000). |
| (summation) | [Pathway:8851907] MET activates PI3K/AKT signaling [Homo sapiens] |
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No pathways have been reviewed or authored by MET binds and phosphorylates the adapter protein GAB1, thus ... (8875933)
