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Details on Person DOCK7 activates RAC1

Class:IdBlackBoxEvent:8875591
_displayNameDOCK7 activates RAC1
_doReleaseTRUE
_timestamp2016-07-19 17:47:21
authored[InstanceEdit:8876386] Orlic-Milacic, Marija, 2016-06-14
catalystActivity[CatalystActivity:8875590] guanyl-nucleotide exchange factor activity of HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:(DOCK7) [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:8875589] Orlic-Milacic, Marija, 2016-06-07
edited[InstanceEdit:8876386] Orlic-Milacic, Marija, 2016-06-14
input[Complex:5674631] RAC1:GDP [plasma membrane] [Homo sapiens]
[SimpleEntity:29438] GTP [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:8875583] Guanine nucleotide exchange factor Dock7 mediates HGF-induced glioblastoma cell invasion via Rac activation
modified[InstanceEdit:8875595] Orlic-Milacic, Marija, 2016-06-07
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8931694] Orlic-Milacic, Marija, 2016-07-18
[InstanceEdit:8931945] Orlic-Milacic, Marija, 2016-07-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameDOCK7 activates RAC1
output[Complex:442641] RAC1:GTP [plasma membrane] [Homo sapiens]
[SimpleEntity:29420] GDP [cytosol]
precedingEvent
releaseDate2016-09-19
reviewed[InstanceEdit:8931695] Heynen, Guustaaf, 2016-07-11
[InstanceEdit:8931697] Birchmeier, Walter, 2016-07-11
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8913769] R-HSA-8875591.2
summation[Summation:8875593] DOCK7, recruited to the activated MET receptor complex throu...
(hasEvent)[Pathway:8875555] MET activates RAP1 and RAC1 [Homo sapiens]
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