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Details on Person Crk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions
| Class:Id | LiteratureReference:8875559 |
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| _displayName | Crk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions |
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| _timestamp | 2016-06-07 19:52:53 |
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| author | [Person:5218678] Lamorte, Louie
[Person:8875557] Royal, Isabelle
[Person:8875552] Naujokas, Monica
[Person:3108186] Park, Morag |
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| created | [InstanceEdit:8875560] Orlic-Milacic, Marija, 2016-06-07 |
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| journal | Mol. Biol. Cell |
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| pages | 1449-61 |
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| pubMedIdentifier | 12006644 |
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| title | Crk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions |
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| volume | 13 |
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| year | 2002 |
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| (literatureReference) | [Complex:8875561] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] [Homo sapiens]
[Pathway:6806834] Signaling by MET [Homo sapiens]
[Pathway:8875555] MET activates RAP1 and RAC1 [Homo sapiens]
[Reaction:8875558] RAPGEF1 binds CRK,CRKL [Homo sapiens]
[Reaction:8875568] RAPGEF1 activates RAP1 [Homo sapiens]
[BlackBoxEvent:8875576] CRK,CRKL recruits RAC1 GEF to activated MET [Homo sapiens]
[Pathway:8875878] MET promotes cell motility [Homo sapiens] |
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No pathways have been reviewed or authored by Crk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions (8875559)
