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Details on Person Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL
| Class:Id | LiteratureReference:8875541 |
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| _displayName | Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL |
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| _timestamp | 2016-06-07 19:21:20 |
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| author | [Person:8875546] Sakkab, D
[Person:8875544] Lewitzky, M
[Person:8875551] Posern, G
[Person:8851911] Schaeper, U
[Person:2534199] Sachs, M
[Person:2534277] Birchmeier, W
[Person:8875538] Feller, S M |
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| created | [InstanceEdit:8875539] Orlic-Milacic, Marija, 2016-06-07 |
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| journal | J. Biol. Chem. |
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| pages | 10772-8 |
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| pubMedIdentifier | 10753869 |
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| title | Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL |
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| volume | 275 |
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| year | 2000 |
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| (literatureReference) | [Pathway:6806834] Signaling by MET [Homo sapiens]
[Reaction:8875540] GAB1 recruits CRK,CRKL to MET [Homo sapiens]
[Pathway:8875555] MET activates RAP1 and RAC1 [Homo sapiens]
[Reaction:8875558] RAPGEF1 binds CRK,CRKL [Homo sapiens]
[Reaction:8875568] RAPGEF1 activates RAP1 [Homo sapiens]
[Pathway:8875878] MET promotes cell motility [Homo sapiens]
[Complex:8875561] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:RAPGEF1 [plasma membrane] [Homo sapiens] |
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