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Query author contributions in Reactome

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Details on Person MET binds LRIG1

Class:IdReaction:8875374
_displayNameMET binds LRIG1
_doReleaseTRUE
_timestamp2016-07-19 17:47:22
authored[InstanceEdit:8876386] Orlic-Milacic, Marija, 2016-06-14
compartment[Compartment:876] plasma membrane
created[InstanceEdit:8875373] Orlic-Milacic, Marija, 2016-06-03
edited[InstanceEdit:8876386] Orlic-Milacic, Marija, 2016-06-14
input[EntityWithAccessionedSequence:197745] LRIG1 [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:419603] MET [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:8875389] LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy
[LiteratureReference:8875397] USP8 modulates ubiquitination of LRIG1 for Met degradation
[LiteratureReference:8875387] Cbl-independent degradation of Met: ways to avoid agonism of bivalent Met-targeting antibody
modified[InstanceEdit:8875411] Orlic-Milacic, Marija, 2016-06-03
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8931694] Orlic-Milacic, Marija, 2016-07-18
[InstanceEdit:8931945] Orlic-Milacic, Marija, 2016-07-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameMET binds LRIG1
output[Complex:8875375] MET:LRIG1 [plasma membrane] [Homo sapiens]
releaseDate2016-09-19
reviewed[InstanceEdit:8931695] Heynen, Guustaaf, 2016-07-11
[InstanceEdit:8931697] Birchmeier, Walter, 2016-07-11
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8899339] R-HSA-8875374.2
summation[Summation:8875403] LRIG1 can bind the MET receptor in the absence of HGF-mediat...
(hasEvent)[Pathway:6807004] Negative regulation of MET activity [Homo sapiens]
(precedingEvent)[Reaction:8875431] LRIG1 undergoes ubiquitination [Homo sapiens]
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No pathways have been reviewed or authored by MET binds LRIG1 (8875374)