Reactome: A Curated Pathway Database
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Details on Person CREB3L4 (CREB4) is observed in the endoplasmic reticulum (ER...

Class:IdSummation:8874811
_displayNameCREB3L4 (CREB4) is observed in the endoplasmic reticulum (ER...
_timestamp2016-07-11 15:24:49
created[InstanceEdit:8874818] May, Bruce, 2016-05-29
modified[InstanceEdit:8878592] May, Bruce, 2016-07-11
textCREB3L4 (CREB4) is observed in the endoplasmic reticulum (ER) and the Golgi (Stirling and O'Hare 2006). Based on homologous transcription factors possessing transmembrane domains, CREB3L4 is inferred to traffic from the ER to the Golgi where it is activated by cleavage. Stress caused by dithiothreitol causes trafficking of CREB3L4 to the Golgi but cleavage by MBTPS1 (S1P) is not observed (Stirling and O'Hare 2006).
(summation)[BlackBoxEvent:8874209] CREB3L4 translocates from the endoplasmic reticulum membrane to the Golgi membrane [Homo sapiens]
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