Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person EGFR gene expression is stimulated by TFAP2C

Class:Id	BlackBoxEvent:8874797
_displayName	EGFR gene expression is stimulated by TFAP2C
_doRelease	TRUE
_timestamp	2016-08-18 14:28:45
authored	[InstanceEdit:8864334] Orlic-Milacic, Marija, 2016-03-14
compartment	[Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created	[InstanceEdit:8874791] Orlic-Milacic, Marija, 2016-05-27
edited	[InstanceEdit:8864334] Orlic-Milacic, Marija, 2016-03-14
input	[EntityWithAccessionedSequence:8874800] EGFR gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8874801] The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis [LiteratureReference:8874784] EGFR Is Regulated by TFAP2C in Luminal Breast Cancer and Is a Target for Vandetanib
modified	[InstanceEdit:8874808] Orlic-Milacic, Marija, 2016-05-27 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8935913] Orlic-Milacic, Marija, 2016-08-15 [InstanceEdit:8936385] Orlic-Milacic, Marija, 2016-08-18 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	EGFR gene expression is stimulated by TFAP2C
output	[EntityWithAccessionedSequence:179837] EGFR [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:8874789] TFAP2C homodimer binds the EGFR gene promoter [Homo sapiens] [Reaction:8864278] AP-2 (TFAP2) transcription factors form homo- and heterodimers [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:8874804] Positive gene expression regulation by 'TFAP2C homodimer:EGFR gene [nucleoplasm]'
regulationReference	[RegulationReference:9642471] Positive gene expression regulation by 'TFAP2C homodimer:EGFR gene [nucleoplasm]' The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis
releaseDate	2016-09-19
reviewed	[InstanceEdit:8874793] Bogachek, Maria V, 2016-05-17 [InstanceEdit:8874798] Weigel, Ronald J, 2016-05-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8901499] R-HSA-8874797.4
summation	[Summation:8874806] Binding of TFAP2C homodimers to the EGFR gene promoter regio...
(hasEvent)	[Pathway:8866910] TFAP2 (AP-2) family regulates transcription of growth factors and their receptors [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by EGFR gene expression is stimulated by TFAP2C (8874797)