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Details on Person TTPA transports alpha-TOH from lysosomal membrane to plasma membrane

Class:IdReaction:8874705
_displayNameTTPA transports alpha-TOH from lysosomal membrane to plasma membrane
_doReleaseTRUE
_timestamp2025-08-12 22:18:04
authored[InstanceEdit:8874737] Jassal, Bijay, 2016-05-26
catalystActivity[CatalystActivity:9948348] lipid transfer activity of TTPA [cytosol]
catalystActivityReference[CatalystActivityReference:9948350] lipid transfer activity of TTPA [cytosol] Intracellular trafficking of vitamin E in hepatocytes: the role of tocopherol transfer protein
compartment[Compartment:70101] cytosol
[Compartment:17938] lysosomal membrane
[Compartment:876] plasma membrane
created[InstanceEdit:8874737] Jassal, Bijay, 2016-05-26
edited[InstanceEdit:8874737] Jassal, Bijay, 2016-05-26
input[SimpleEntity:8874708] alpha-TOH [lysosomal membrane]
internalReviewed[InstanceEdit:9948354] D'Eustachio, Peter, 2025-05-19
isChimericFALSE
literatureReference[LiteratureReference:8874707] Human alpha-tocopherol transfer protein: cDNA cloning, expression and chromosomal localization
[LiteratureReference:8874733] Human plasma phospholipid transfer protein accelerates exchange/transfer of alpha-tocopherol between lipoproteins and cells
[LiteratureReference:8874731] Intracellular trafficking of vitamin E in hepatocytes: the role of tocopherol transfer protein
[LiteratureReference:8874721] Intracellular transport of fat-soluble vitamins A and E
[LiteratureReference:8874717] Complexity of vitamin E metabolism
[LiteratureReference:8874727] Human plasma vitamin E kinetics demonstrate rapid recycling of plasma RRR-alpha-tocopherol
modified[InstanceEdit:8874753] Jassal, Bijay, 2016-05-27
[InstanceEdit:8879142] Jassal, Bijay, 2016-07-15
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8932134] Jassal, Bijay, 2016-07-21
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9948349] D'Eustachio, Peter, 2025-05-19
[InstanceEdit:9948355] D'Eustachio, Peter, 2025-05-19
[InstanceEdit:9962971] D'Eustachio, Peter, 2025-08-12
nameTTPA transports alpha-TOH from lysosomal membrane to plasma membrane
output[SimpleEntity:8874706] alpha-TOH [plasma membrane]
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2016-09-19
reviewed[InstanceEdit:8879141] D'Eustachio, Peter, 2016-07-15
[InstanceEdit:9962972] Hill, David P, 2025-08-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8910030] R-HSA-8874705.4
structureModified[InstanceEdit:9948349] D'Eustachio, Peter, 2025-05-19
summation[Summation:8874702] Alpha-tocopherol (alpha-TOH) is the major form of fat-solubl...
(hasEvent)[Pathway:8877627] Vitamin E transport [Homo sapiens]
(replacementInstances)[_Deleted:9948352] Deletion of instance: 8874718
(updatedInstance)[_UpdateTracker:9953755] Update Tracker - [Reaction:8874705] TTPA transports alpha-TOH from lysosomal membrane to plasma membrane - v93:[add_removeInput, add_removeOutput, modifyText, removeCatalystActivity]
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