Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person RGGT:CHM binds RABs

Class:Id	Reaction:8870466
_displayName	RGGT:CHM binds RABs
_doRelease	TRUE
_timestamp	2016-11-17 21:22:44
authored	[InstanceEdit:8875718] Rothfels, Karen, 2016-06-08
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:8870468] Rothfels, Karen, 2016-05-09
edited	[InstanceEdit:8875718] Rothfels, Karen, 2016-06-08
input	[Complex:8870462] RABGGTA:RABGGTB:CHMs:GGPP [cytosol] [Homo sapiens] [Complex:8875311] RABs:GDP [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8874649] Nucleotide dependence of Rab geranylgeranylation. Rab escort protein interacts preferentially with GDP-bound Rab [LiteratureReference:8935810] cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein [LiteratureReference:8935807] Allosteric regulation of substrate binding and product release in geranylgeranyltransferase type II [LiteratureReference:6801119] Phosphoisoprenoids modulate association of Rab geranylgeranyltransferase with REP-1 [LiteratureReference:6801102] Rab geranylgeranylation occurs preferentially via the pre-formed REP-RGGT complex and is regulated by geranylgeranyl pyrophosphate [LiteratureReference:8874103] Rab escort protein-1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes [LiteratureReference:8874101] Mechanism of digeranylgeranylation of Rab proteins. Formation of a complex between monogeranylgeranyl-Rab and Rab escort protein
modified	[InstanceEdit:8874112] Rothfels, Karen, 2016-05-20 [InstanceEdit:8875340] Rothfels, Karen, 2016-06-02 [InstanceEdit:8875724] Rothfels, Karen, 2016-06-08 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8933445] Rothfels, Karen, 2016-08-04 [InstanceEdit:8936086] Rothfels, Karen, 2016-08-16 [InstanceEdit:8936122] Rothfels, Karen, 2016-08-16 [InstanceEdit:8943257] Rothfels, Karen, 2016-10-24 [InstanceEdit:8948925] Rothfels, Karen, 2016-11-17 [InstanceEdit:8948931] Rothfels, Karen, 2016-11-17 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RGGT:CHM binds RABs
output	[Complex:8870467] RGGT:CHMs:RABs:GDP [cytosol] [Homo sapiens]
precedingEvent	[Reaction:8870465] RGGT binds the RAB-binding subunit [Homo sapiens] [Reaction:8870461] RABGGTA and RABGGTB bind [Homo sapiens]
releaseDate	2016-12-12
reviewed	[InstanceEdit:8933435] Palsuledesai, Charuta C, 2016-08-04
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8897516] R-HSA-8870466.2
summation	[Summation:8874105] CHM and CHML are the substrate-binding subunits of the RAB g...
(hasEvent)	[Pathway:8873719] RAB geranylgeranylation [Homo sapiens]
(precedingEvent)	[Reaction:8870469] RGGT geranylgeranylates RAB proteins [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by RGGT:CHM binds RABs (8870466)