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Details on Person RABGGTA and RABGGTB bind

Class:IdReaction:8870461
_displayNameRABGGTA and RABGGTB bind
_doReleaseTRUE
_timestamp2016-11-17 21:22:28
authored[InstanceEdit:8875718] Rothfels, Karen, 2016-06-08
compartment[Compartment:70101] cytosol
created[InstanceEdit:8870459] Rothfels, Karen, 2016-05-09
edited[InstanceEdit:8875718] Rothfels, Karen, 2016-06-08
input[EntityWithAccessionedSequence:8870418] RABGGTA [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:8870419] RABGGTB [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:8870369] Interaction of farnesylated PRL-2, a protein-tyrosine phosphatase, with the beta-subunit of geranylgeranyltransferase II
[LiteratureReference:8870364] Structure, regulation and cellular functions of Rab geranylgeranyl transferase and its cellular partner Rab Escort Protein
[LiteratureReference:6801102] Rab geranylgeranylation occurs preferentially via the pre-formed REP-RGGT complex and is regulated by geranylgeranyl pyrophosphate
[LiteratureReference:8870365] Thematic review series: lipid posttranslational modifications. geranylgeranylation of Rab GTPases
[LiteratureReference:8855098] Rab GTPases as coordinators of vesicle traffic
[LiteratureReference:8871106] Rab proteins and the compartmentalization of the endosomal system
[LiteratureReference:8933172] Rab13 Traffics on Vesicles Independent of Prenylation
modified[InstanceEdit:8874114] Rothfels, Karen, 2016-05-20
[InstanceEdit:8875720] Rothfels, Karen, 2016-06-08
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8933442] Rothfels, Karen, 2016-08-04
[InstanceEdit:8935804] Rothfels, Karen, 2016-08-15
[InstanceEdit:8936119] Rothfels, Karen, 2016-08-16
[InstanceEdit:8943254] Rothfels, Karen, 2016-10-24
[InstanceEdit:8948922] Rothfels, Karen, 2016-11-17
[InstanceEdit:8948928] Rothfels, Karen, 2016-11-17
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameRABGGTA and RABGGTB bind
output[Complex:8870460] RABGGTA:RABGGTB [cytosol] [Homo sapiens]
regulatedBy[NegativeRegulation:8873723] Negative regulation by 'FarC-PTP4A2:RABGGTB [cytosol]'
releaseDate2016-12-12
reviewed[InstanceEdit:8933435] Palsuledesai, Charuta C, 2016-08-04
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8915165] R-HSA-8870461.3
summation[Summation:8870452] RABGGTA and RABGGTB are the two catalytic subunits of a trim...
(hasEvent)[Pathway:8873719] RAB geranylgeranylation [Homo sapiens]
(precedingEvent)[Reaction:8870465] RGGT binds the RAB-binding subunit [Homo sapiens]
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No pathways have been reviewed or authored by RABGGTA and RABGGTB bind (8870461)
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