Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6

Class:IdReaction:8869506
_displayNameTNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6
_doReleaseTRUE
_timestamp2016-05-19 16:46:09
authored[InstanceEdit:5688416] Jupe, Steve, 2015-04-16
catalystActivity[CatalystActivity:8869507] K63-linked deubiquitinase activity of OTUD7B,TNFAIP3,ZRANB1:K63polyUb-TRAF6 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:8869502] Jupe, Steve, 2016-05-05
edited[InstanceEdit:8869523] Jupe, Steve, 2016-05-05
input[Complex:8869500] OTUD7B,TNFAIP3,ZRANB1:K63polyUb-TRAF6 [cytosol] [Homo sapiens]
[SimpleEntity:29356] H2O [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:5690862] The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
modified[InstanceEdit:8869523] Jupe, Steve, 2016-05-05
[InstanceEdit:8869637] Jupe, Steve, 2016-05-06
[InstanceEdit:8871338] Jupe, Steve, 2016-05-16
[InstanceEdit:8871616] Weiser, JD
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameTNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6
output[Complex:6783276] OTUD7B,TNFAIP3,ZRANB1:TRAF6 [cytosol] [Homo sapiens]
[Polymer:450152] K63polyUb [cytosol] [Homo sapiens]
releaseDate2016-06-15
reviewed[InstanceEdit:8871339] Meldal, Birgit, 2016-05-16
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8873364] R-HSA-8869506.3
summation[Summation:8869503] TNFAIP3 can remove K63-linked ubiquitin from TRAF6, which te...
(hasEvent)[Pathway:5689896] Ovarian tumor domain proteases [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (8869506)
Follow Reactome