Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Oxidative stress, manifested through accumulation of reactiv...
| Class:Id | Summation:8868596 |
|---|---|
| _displayName | Oxidative stress, manifested through accumulation of reactiv... |
| _timestamp | 2016-04-22 18:44:08 |
| created | [InstanceEdit:8868597] Orlic-Milacic, Marija, 2016-04-22 |
| modified | [InstanceEdit:8868600] Orlic-Milacic, Marija, 2016-04-22 [InstanceEdit:8868681] Orlic-Milacic, Marija, 2016-04-22 |
| text | Oxidative stress, manifested through accumulation of reactive oxygen species in the cell, is one of the hallmarks of Alzheimer's disease. Based on mouse model studies, CDK5, aberrantly activated by binding to p25, phosphorylates the peroxide reductase PRDX1 on a conserved threonine residue T90, thus inactivating it and contributing to ROS accumulation (Sun et al. 2008). |
| (summation) | [Reaction:8868567] CDK5:p25 phosphorylates PRDX1 [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Oxidative stress, manifested through accumulation of reactiv... (8868596)
