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Details on Person Cdk5:p25 phosphorylates lamin B1

Class:Id	Reaction:8868383
_displayName	Cdk5:p25 phosphorylates lamin B1
_doRelease	TRUE
_timestamp	2016-07-15 23:49:58
authored	[InstanceEdit:8862798] Shah, Kavita, 2016-02-23
catalystActivity	[CatalystActivity:8868355] protein serine/threonine kinase activity of Cdk5:p25 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8868382] Orlic-Milacic, Marija, 2016-04-20
edited	[InstanceEdit:8870556] Orlic-Milacic, Marija, 2016-05-10
input	[Complex:8868375] Lmnb1 dimer [nucleoplasm] [Mus musculus] [SimpleEntity:29358] ATP [nucleoplasm] [SimpleEntity:29358] ATP [nucleoplasm] [SimpleEntity:29358] ATP [nucleoplasm] [SimpleEntity:29358] ATP [nucleoplasm]
isChimeric	FALSE
literatureReference	[LiteratureReference:8868146] Nuclear envelope dispersion triggered by deregulated Cdk5 precedes neuronal death
modified	[InstanceEdit:8868387] Orlic-Milacic, Marija, 2016-04-20 [InstanceEdit:8870557] Orlic-Milacic, Marija, 2016-05-10 [InstanceEdit:8875080] Orlic-Milacic, Marija, 2016-06-01 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Cdk5:p25 phosphorylates lamin B1
output	[SimpleEntity:113582] ADP [nucleoplasm] [SimpleEntity:113582] ADP [nucleoplasm] [SimpleEntity:113582] ADP [nucleoplasm] [SimpleEntity:113582] ADP [nucleoplasm] [Complex:8868379] p-S24,S394-Lamin B1 dimer [nucleoplasm] [Mus musculus]
releaseDate	2016-09-19
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:8908453] R-MMU-8868383.2
summation	[Summation:8868385] In a mouse Alzheimer's disease model, nuclear fragmentation,...
(inferredFrom)	[Reaction:8868340] CDK5:p25 phosphorylates lamin B1 [Homo sapiens]
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No pathways have been reviewed or authored by Cdk5:p25 phosphorylates lamin B1 (8868383)