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Details on Person PTPN3 binds p-T183,Y185 MAPK12

Class:IdReaction:8867654
_displayNamePTPN3 binds p-T183,Y185 MAPK12
_doReleaseTRUE
_timestamp2020-05-04 20:38:29
authored[InstanceEdit:8865229] Rothfels, Karen, 2016-03-21
compartment[Compartment:70101] cytosol
created[InstanceEdit:8867652] Rothfels, Karen, 2016-04-15
edited[InstanceEdit:8865229] Rothfels, Karen, 2016-03-21
input[EntityWithAccessionedSequence:171021] p-T183,Y185-MAPK12 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:8867650] PTPN3 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:8867629] Essential role of p38gamma in K-Ras transformation independent of phosphorylation
[LiteratureReference:8867632] PTPH1 dephosphorylates and cooperates with p38gamma MAPK to increase ras oncogenesis through PDZ-mediated interaction
[LiteratureReference:8867646] Reciprocal allosteric regulation of p38γ and PTPN3 involves a PDZ domain-modulated complex formation
modified[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:9674641] Rothfels, Karen, 2020-01-17
[InstanceEdit:9676028] Rothfels, Karen, 2020-02-06
[InstanceEdit:9676768] Rothfels, Karen, 2020-02-20
[InstanceEdit:9686661] Rothfels, Karen, 2020-05-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePTPN3 binds p-T183,Y185 MAPK12
output[Complex:8867651] PTPN3:p-T183,Y185-MAPK12 [cytosol] [Homo sapiens]
releaseDate2020-06-10
reviewed[InstanceEdit:9686656] Gavathiotis, Evripidis, 2020-05-04
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8881707] R-HSA-8867654.2
summation[Summation:8867653] PTPN3 is a protein phosphatase that dephosphorylates MAPK12,...
(hasEvent)[Pathway:5675221] Negative regulation of MAPK pathway [Homo sapiens]
(precedingEvent)[Reaction:8867658] PTPN3 dephosphorylates MAPK12 [Homo sapiens]
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No pathways have been reviewed or authored by PTPN3 binds p-T183,Y185 MAPK12 (8867654)