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Details on Person TTLL3, TTLL8, TTLL10 polyglycylate tubulin

Class:Id	Reaction:8867370
_displayName	TTLL3, TTLL8, TTLL10 polyglycylate tubulin
_doRelease	TRUE
_timestamp	2019-07-24 13:52:40
authored	[InstanceEdit:8867403] Jupe, Steve, 2016-04-14
catalystActivity	[CatalystActivity:8867454] protein-glycine ligase activity of TTLL3,TTLL8,TTLL10 [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:8867403] Jupe, Steve, 2016-04-14
edited	[InstanceEdit:8955880] D'Eustachio, Peter, 2017-01-13
goBiologicalProcess	[GO_BiologicalProcess:2673] protein polyglycylation
input	[Complex:190599] Microtubule [cytosol] [Homo sapiens] [SimpleEntity:29424] Gly [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:8866054] TTLL10 is a protein polyglycylase that can modify nucleosome assembly protein 1 [LiteratureReference:8867451] TTLL3 Is a tubulin glycine ligase that regulates the assembly of cilia [LiteratureReference:8866102] Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation
modified	[InstanceEdit:8878478] Jupe, Steve, 2016-07-05 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8955328] D'Eustachio, Peter, 2017-01-10 [InstanceEdit:8955518] D'Eustachio, Peter, 2017-01-11 [InstanceEdit:8955871] D'Eustachio, Peter, 2017-01-13 [InstanceEdit:8956249] D'Eustachio, Peter, 2017-01-18 [InstanceEdit:8957282] Jupe, Steve, 2017-01-24 [InstanceEdit:8982723] Jupe, Steve, 2017-03-22 [InstanceEdit:9655243] D'Eustachio, Peter, 2019-07-23 [InstanceEdit:9655301] D'Eustachio, Peter, 2019-07-24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TTLL3, TTLL8, TTLL10 polyglycylate tubulin
output	[Complex:8982726] Polyglycylated microtubule [cytosol] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29372] Pi [cytosol]
releaseDate	2017-03-27
reviewed	[InstanceEdit:8956247] Jassal, Bijay, 2017-01-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8900741] R-HSA-8867370.4
summation	[Summation:8867371] Tubulin is modified by glutamylation and glycylation, the ad...
(hasEvent)	[Pathway:8955332] Carboxyterminal post-translational modifications of tubulin [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9777636] Update Tracker - [Reaction:8867370] TTLL3, TTLL8, TTLL10 polyglycylate tubulin - v70:[add_removeInput, add_removeOutput] [_UpdateTracker:9781196] Update Tracker - [Reaction:8867370] TTLL3, TTLL8, TTLL10 polyglycylate tubulin - v61:[add_removeOutput, modifyText]
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No pathways have been reviewed or authored by TTLL3, TTLL8, TTLL10 polyglycylate tubulin (8867370)