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Details on Person ub-CFTR F508del:ERAD complex [endoplasmic reticulum membrane]

Class:IdComplex:8866846
_displayNameub-CFTR F508del:ERAD complex [endoplasmic reticulum membrane]
_timestamp2019-01-15 13:52:35
compartment[Compartment:12045] endoplasmic reticulum membrane
created[InstanceEdit:8866845] Rothfels, Karen, 2016-04-04
disease[Disease:5678942] cystic fibrosis
hasComponent
isChimericFALSE
modified[InstanceEdit:8871616] Weiser, JD
[InstanceEdit:9634795] Rothfels, Karen, 2019-01-15
nameub-CFTR F508del:ERAD complex
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8872182] R-HSA-8866846.3
(diseaseEntity)[EntityFunctionalStatus:9630134] gain_of_function of ub-CFTR F508del:ERAD complex [endoplasmic reticulum membrane]
(input)[Reaction:8866854] VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol [Homo sapiens]
(output)[Reaction:8866856] RNF5 and RNF185 ubiquitinate CFTR F508del [Homo sapiens]
(updatedInstance)[_UpdateTracker:9897064] Update Tracker - [Complex:8866846] ub-CFTR F508del:ERAD complex [endoplasmic reticulum membrane] - v61:[updateContainedComponent]
[_UpdateTracker:9900026] Update Tracker - [Complex:8866846] ub-CFTR F508del:ERAD complex [endoplasmic reticulum membrane] - v67:[updateContainedComponent]
[_UpdateTracker:9900092] Update Tracker - [Complex:8866846] ub-CFTR F508del:ERAD complex [endoplasmic reticulum membrane] - v68:[add_removeHasComponent]
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No pathways have been reviewed or authored by ub-CFTR F508del:ERAD complex [endoplasmic reticulum membrane] (8866846)
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