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Details on Person PAF1C [nucleoplasm]

Class:Id	Complex:8866690
_displayName	PAF1C [nucleoplasm]
_timestamp	2016-05-19 16:41:36
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8866699] May, Bruce, 2016-04-03
hasComponent	[EntityWithAccessionedSequence:3322360] CDC73 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8866694] CTR9 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:3322361] LEO1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8866689] PAF1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8866693] RTF1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8866696] WDR61 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8866695] RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II
modified	[InstanceEdit:8871616] Weiser, JD
name	PAF1C
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8872155] R-HSA-8866690.2
(hasComponent)	[Complex:112433] Elongation complex [nucleoplasm] [Homo sapiens] [Complex:113719] Processive elongation complex [nucleoplasm] [Homo sapiens] [Complex:113720] Paused processive elongation complex [nucleoplasm] [Homo sapiens] [Complex:113721] Arrested processive elongation complex [nucleoplasm] [Homo sapiens] [Complex:113722] Aborted elongation complex after arrest [nucleoplasm] [Homo sapiens] [Complex:113724] Elongation complex prior to separation [nucleoplasm] [Homo sapiens] [Complex:113726] Elongation complex with separated and uncleaved transcript [nucleoplasm] [Homo sapiens] [Complex:8942094] PAF1c:WAC:RNF20:RNF40:Ub:UBE2A,B:HIST1H2B [nucleoplasm] [Homo sapiens] [Complex:9921884] NS5:PAF1C [nucleoplasm] [Homo sapiens] [Complex:9943563] CHD1:H3K4 nucleosome:FACT complex:U2 snRNP complex:PAF1C complex [nucleoplasm] [Homo sapiens]
(input)	[Reaction:112379] Recruitment of elongation factors to form elongation complex [Homo sapiens] [Reaction:8942099] RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B [Homo sapiens] [Reaction:9921879] NS5 binds PAF1C [Homo sapiens] [Reaction:9943567] CHD1:H3K4me3 interacts with post-initiation transcription complexes [Homo sapiens]
(output)	[Reaction:113429] Elongating transcript encounters a lesion in the template [Homo sapiens] [BlackBoxEvent:8942101] RNF20:RNF40 monoubiquitinates Histone H2B [Homo sapiens]
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No pathways have been reviewed or authored by PAF1C [nucleoplasm] (8866690)