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Details on Person Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase

Class:Id	LiteratureReference:8866603
_displayName	Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase
_timestamp	2016-04-01 21:26:24
author	[Person:8866605] Powell, Rebecca D [Person:8866617] Holland, Paul J [Person:3244615] Hollis, Thomas [Person:3244652] Perrino, Fred W
created	[InstanceEdit:8866600] D'Eustachio, Peter, 2016-04-01
journal	J. Biol. Chem.
pages	43596-600
pubMedIdentifier	22069334
title	Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase
volume	286
year	2011
(literatureReference)	[Reaction:8866601] SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate [Homo sapiens] [RegulationReference:9641384] Positive regulation by 'dGTP [nucleoplasm]' HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase [CatalystActivityReference:9644078] triphosphoric monoester hydrolase activity of SAMHD1:Zn2+ tetramer [nucleoplasm] HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
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No pathways have been reviewed or authored by Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase (8866603)