Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Rothfels, Karen, 2016-04-01

Class:IdInstanceEdit:8866556
_displayNameRothfels, Karen, 2016-04-01
_timestamp2016-04-01 20:18:29
author[Person:1226097] Rothfels, Karen
dateTime2016-04-02 00:18:17
(authored)[Reaction:8866546] RNF5 and RNF185 ubiquitinate misfolded CFTR [Homo sapiens]
[Reaction:8866551] CFTR binds components of the ERAD machinery for ubiquitination and degradation [Homo sapiens]
[BlackBoxEvent:8866851] CFTR transits to the plasma membrane [Homo sapiens]
[Reaction:8866854] VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol [Homo sapiens]
[Reaction:8866856] RNF5 and RNF185 ubiquitinate CFTR F508del [Homo sapiens]
[Reaction:8866857] CFTR F508del binds components of the ERAD machinery for ubiquitination and degradation [Homo sapiens]
[BlackBoxEvent:8866858] CFTR F508del is degraded by the 26S proteasome [Homo sapiens]
(edited)[Reaction:8866551] CFTR binds components of the ERAD machinery for ubiquitination and degradation [Homo sapiens]
[BlackBoxEvent:8866851] CFTR transits to the plasma membrane [Homo sapiens]
[Reaction:8866854] VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol [Homo sapiens]
[Reaction:8866856] RNF5 and RNF185 ubiquitinate CFTR F508del [Homo sapiens]
[Reaction:8866857] CFTR F508del binds components of the ERAD machinery for ubiquitination and degradation [Homo sapiens]
[BlackBoxEvent:8866858] CFTR F508del is degraded by the 26S proteasome [Homo sapiens]
(modified)[PathwayDiagram:662639] Diagram of ABC-family protein mediated transport, Defective ABCB4 causes PFIC3, ICP3 and GBD1, Defective CFTR causes cystic fibrosis, Defective ABCG5 causes sitosterolemia, Defective ABCG8 causes GBD4 and sitosterolemia, Defective ABCA12 causes ARCI4B, Variant ABCB1 increases susceptibility to inflammatory bowel disease 13, Defective ABCB6 causes MCOPCB7, Defective ABCA3 causes SMDP3, Defective ABCD1 causes ALD, Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome, and Defective ABCC6 causes PXE
[Change default viewing format]
No pathways have been reviewed or authored by Rothfels, Karen, 2016-04-01 (8866556)
Follow Reactome