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Details on Person Rothfels, Karen, 2016-04-01

Class:IdInstanceEdit:8866543
_displayNameRothfels, Karen, 2016-04-01
_timestamp2016-04-01 20:18:18
author[Person:1226097] Rothfels, Karen
dateTime2016-04-02 00:18:05
(authored)[Reaction:8866542] VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol [Homo sapiens]
[BlackBoxEvent:8866553] misfolded CFTR is degraded by the 26S proteasome [Homo sapiens]
[Reaction:8866854] VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol [Homo sapiens]
[BlackBoxEvent:8866858] CFTR F508del is degraded by the 26S proteasome [Homo sapiens]
(created)[Reaction:8866542] VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol [Homo sapiens]
[Summation:8866544] Retrotranslocation of the misfolded CFTR likely depends on t...
[Summation:8866545] RNF5 and RNF185 ubiquitinate misfolded CFTR as part of the r...
[Reaction:8866546] RNF5 and RNF185 ubiquitinate misfolded CFTR [Homo sapiens]
[CatalystActivity:8866547] ubiquitin protein ligase activity of misfolded CFTR:ERAD complex [endoplasmic reticulum membrane]
(edited)[Reaction:8866542] VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol [Homo sapiens]
[BlackBoxEvent:8866553] misfolded CFTR is degraded by the 26S proteasome [Homo sapiens]
[Reaction:8866854] VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol [Homo sapiens]
[BlackBoxEvent:8866858] CFTR F508del is degraded by the 26S proteasome [Homo sapiens]
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No pathways have been reviewed or authored by Rothfels, Karen, 2016-04-01 (8866543)