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Details on Person Ub-misfolded nascent CFTR [cytosol]

Class:Id	Complex:8866534
_displayName	Ub-misfolded nascent CFTR [cytosol]
_timestamp	2019-01-15 13:52:17
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:8866532] Rothfels, Karen, 2016-04-01
hasComponent	[EntityWithAccessionedSequence:8868730] misfolded CFTR [endoplasmic reticulum membrane] [Homo sapiens] [DefinedSet:113595] Ub [cytosol] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:8868728] Rothfels, Karen, 2016-04-22 [InstanceEdit:8868749] Rothfels, Karen, 2016-04-22 [InstanceEdit:8871616] Weiser, JD [InstanceEdit:9634791] Rothfels, Karen, 2019-01-15
name	Ub-misfolded nascent CFTR
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8872149] R-HSA-8866534.3
(hasComponent)	[Complex:8866535] Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] [Homo sapiens]
(hasMember)	[DefinedSet:9641117] Ub-Misfolded Proteins [cytosol] [Homo sapiens]
(input)	[BlackBoxEvent:8866553] misfolded CFTR is degraded by the 26S proteasome [Homo sapiens]
(normalEntity)	[EntityFunctionalStatus:9630131] gain_of_function of ub-CFTR F508del [cytosol]
(output)	[Reaction:8866542] VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9897297] Update Tracker - [Complex:8866534] Ub-misfolded nascent CFTR [cytosol] - v61:[updateContainedComponent] [_UpdateTracker:9900241] Update Tracker - [Complex:8866534] Ub-misfolded nascent CFTR [cytosol] - v68:[add_removeHasComponent]
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No pathways have been reviewed or authored by Ub-misfolded nascent CFTR [cytosol] (8866534)