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Details on Person AP-2 dileucine-containing cargo [plasma membrane]

Class:Id	DefinedSet:8866234
_displayName	AP-2 dileucine-containing cargo [plasma membrane]
_timestamp	2016-05-19 16:40:18
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:8866233] Rothfels, Karen, 2016-03-29
hasMember	[EntityWithAccessionedSequence:198171] CD3D [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:197917] CD3G [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:8864461] VAMP4 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:167542] CD4 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:429140] SLC2A8 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:8864566] SCARB2 [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:8864613] A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains [LiteratureReference:8864661] The gamma/sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site [LiteratureReference:8864615] A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex [LiteratureReference:8864637] Endocytosis of the glucose transporter GLUT8 is mediated by interaction of a dileucine motif with the beta2-adaptin subunit of the AP-2 adaptor complex [LiteratureReference:8864650] Lysosomal targeting of Limp II membrane glycoprotein requires a novel Leu-Ile motif at a particular position in its cytoplasmic tail
modified	[InstanceEdit:8871616] Weiser, JD
name	AP-2 dileucine-containing cargo
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8871814] R-HSA-8866234.2
(hasMember)	[DefinedSet:8866235] AP-2 cargo [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by AP-2 dileucine-containing cargo [plasma membrane] (8866234)