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Details on Person MFSD2A transports LPC from extracellular region to plasma membrane

Class:IdReaction:8865637
_displayNameMFSD2A transports LPC from extracellular region to plasma membrane
_doReleaseTRUE
_timestamp2016-07-21 14:12:06
authored[InstanceEdit:8865657] Jassal, Bijay, 2016-03-23
catalystActivity[CatalystActivity:8865644] phospholipid transfer activity of MFSD2A [plasma membrane]
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
[Compartment:70101] cytosol
created[InstanceEdit:8865654] Jassal, Bijay, 2016-03-23
edited[InstanceEdit:8865657] Jassal, Bijay, 2016-03-23
input[SimpleEntity:8865642] LPC (22:6) [extracellular region]
[SimpleEntity:74113] Na+ [extracellular region]
isChimericFALSE
literatureReference[LiteratureReference:8865651] Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome
[LiteratureReference:8865632] Structural insights into the transport mechanism of the human sodium-dependent lysophosphatidylcholine transporter Mfsd2a
[LiteratureReference:8865634] Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid
modified[InstanceEdit:8865680] Jassal, Bijay, 2016-03-23
[InstanceEdit:8866936] Jassal, Bijay, 2016-04-05
[InstanceEdit:8876876] Jassal, Bijay, 2016-06-17
[InstanceEdit:8879142] Jassal, Bijay, 2016-07-15
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8932134] Jassal, Bijay, 2016-07-21
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameMFSD2A transports LPC from extracellular region to plasma membrane
output[SimpleEntity:8865629] LPC (22:6) [cytosol]
[SimpleEntity:83910] Na+ [cytosol]
releaseDate2016-09-19
reviewed[InstanceEdit:8879141] D'Eustachio, Peter, 2016-07-15
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8898971] R-HSA-8865637.2
summation[Summation:8865630] Sodium-dependent lysophosphatidylcholine symporter 1 (MFSD2A...
(hasEvent)[Pathway:1483191] Synthesis of PC [Homo sapiens]
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