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Details on Person Histone reader BRWD1 targets and restricts recombination to the Igk locus
| Class:Id | LiteratureReference:8865615 |
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| _displayName | Histone reader BRWD1 targets and restricts recombination to the Igk locus |
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| _timestamp | 2016-03-23 16:09:32 |
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| author | [Person:5692607] Mandal, Malay
[Person:8865625] Hamel, Keith M
[Person:5692612] Maienschein-Cline, Mark
[Person:8865621] Tanaka, Azusa
[Person:8865623] Teng, Grace
[Person:8865627] Tuteja, Jigyasa H
[Person:8865617] Bunker, Jeffrey J
[Person:8865618] Bahroos, Neil
[Person:3222371] Eppig, John J
[Person:8865624] Schatz, David G
[Person:5692615] Clark, Marcus R |
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| created | [InstanceEdit:8865616] Orlic-Milacic, Marija, 2016-03-23 |
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| journal | Nat. Immunol. |
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| pages | 1094-103 |
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| pubMedIdentifier | 26301565 |
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| title | Histone reader BRWD1 targets and restricts recombination to the Igk locus |
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| volume | 16 |
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| year | 2015 |
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| (literatureReference) | [RegulationReference:9641570] Negative gene expression regulation by '2x(p-STAT5A,p-STAT5B):BRWD1 gene [nucleoplasm]' Histone reader BRWD1 targets and restricts recombination to the Igk locus
[RegulationReference:9642403] Positive regulation by 'BRWD1:AcK9,14-pS10-histone H3 [nucleoplasm]' Histone reader BRWD1 targets and restricts recombination to the Igk locus
[RegulationReference:9642480] Positive regulation by 'BRWD1:AcK9,14-p-S10-histone H3.1 [nucleoplasm]' Histone reader BRWD1 targets and restricts recombination to the Igk locus
[RegulationReference:9642665] Negative regulation by 'p-Stat5 dimer:Brwd1 gene [nucleoplasm]' Histone reader BRWD1 targets and restricts recombination to the Igk locus
[Reaction:8865613] BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 [Homo sapiens]
[Reaction:8865688] Phosphorylated Stat5 dimers bind the Brwd1 gene promoter [Mus musculus]
[BlackBoxEvent:8865699] Brwd1 gene expression is inhibited by p-Stat5 dimers [Mus musculus]
[BlackBoxEvent:8865711] RAG1:RAG2 recombinase binds immunoglobulin kappa locus in a BRWD1-dependent manner [Homo sapiens]
[BlackBoxEvent:8865728] RAG1:RAG2 recombinase binds immunoglobulin kappa locus in a Brwd1-dependent manner [Mus musculus]
[Complex:8865622] 2x(p-STAT5A,p-STAT5B):BRWD1 gene [nucleoplasm] [Homo sapiens] |
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