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Details on Person BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3

Class:Id	Reaction:8865613
_displayName	BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3
_doRelease	TRUE
_timestamp	2017-08-09 12:16:23
authored	[InstanceEdit:8865592] Orlic-Milacic, Marija, 2016-03-23
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8865592] Orlic-Milacic, Marija, 2016-03-23
edited	[InstanceEdit:8865592] Orlic-Milacic, Marija, 2016-03-23 [InstanceEdit:9014125] Duenas, Corina, 2017-07-26
input	[EntityWithAccessionedSequence:8863306] BRWD1 [nucleoplasm] [Homo sapiens] [CandidateSet:8871307] AcK(9,14,18,79)-p(S10,T11)-histone H3 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8865597] Histone recognition and large-scale structural analysis of the human bromodomain family [LiteratureReference:8865615] Histone reader BRWD1 targets and restricts recombination to the Igk locus
modified	[InstanceEdit:8865714] Orlic-Milacic, Marija, 2016-03-23 [InstanceEdit:8870776] Orlic-Milacic, Marija, 2016-05-11 [InstanceEdit:8870836] Orlic-Milacic, Marija, 2016-05-12 [InstanceEdit:8870848] Orlic-Milacic, Marija, 2016-05-12 [InstanceEdit:8871309] Orlic-Milacic, Marija, 2016-05-13 [InstanceEdit:8871310] Orlic-Milacic, Marija, 2016-05-13 [InstanceEdit:8871329] Orlic-Milacic, Marija, 2016-05-13 [InstanceEdit:8871616] Weiser, JD [InstanceEdit:9015191] Duenas, Corina, 2017-08-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3
output	[Complex:8865594] BRWD1:AcK(9,14,18,79)-p(S10,T11)-histone H3 [nucleoplasm] [Homo sapiens]
precedingEvent	[BlackBoxEvent:8865693] BRWD1 gene expression is repressed by STAT5 [Homo sapiens] [Reaction:8865626] p-STAT5 dimers bind the BRWD1 gene promoter [Homo sapiens]
releaseDate	2016-06-15
reviewed	[InstanceEdit:8870773] Mandal, Malay, 2016-05-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8873397] R-HSA-8865613.4
summation	[Summation:8865604] Human Bromodomain and WD repeat-containing protein 1 (BRWD1)...
(hasEvent)	[Pathway:1266695] Interleukin-7 signaling [Homo sapiens] [Pathway:3247509] Chromatin modifying enzymes [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:8865711] RAG1:RAG2 recombinase binds immunoglobulin kappa locus in a BRWD1-dependent manner [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781032] Update Tracker - [Reaction:8865613] BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 - v61:[modifyText]
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No pathways have been reviewed or authored by BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 (8865613)