Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person RUNX1 [nucleoplasm]

Class:IdEntityWithAccessionedSequence:8865295
_displayNameRUNX1 [nucleoplasm]
_timestamp2016-07-15 23:49:55
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:8865296] Orlic-Milacic, Marija, 2016-03-21
endCoordinate453
modified[InstanceEdit:8879177] Wu, G, 2016-07-15
nameRUNX1
Runt-related transcription factor 1
AML1
Oncogene AML-1
Acute myeloid leukemia 1 protein
Core-binding factor subunit alpha-2
CBF-alpha-2
CBFA2
Polyomavirus enhancer-binding protein 2 alpha B subunit
PEA2-alpha B
PEBP2-alpha B
SL3-3 enhancer factor 1 alpha B subunit
SL3/AKV core-binding factor alpha B subunit
RUNX1_HUMAN
referenceEntity[ReferenceGeneProduct:63856] UniProt:Q01196 RUNX1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8907480] R-HSA-8865295.1
startCoordinate1
(activeUnit)[NegativeGeneExpressionRegulation:9604723] Negative gene expression regulation by 'RUNX1:NOTCH4 gene [nucleoplasm]'
(hasComponent)[Complex:8865330] RUNX1:CBFB [nucleoplasm] [Homo sapiens]
[Complex:8865511] RUNX1:Cbfb [nucleoplasm] [Homo sapiens]
[Complex:8937687] p-Y419-SRC:RUNX1 [nucleoplasm] [Homo sapiens]
[Complex:8938868] RUNX1:CCND3,(CCND1,CCND2) [nucleoplasm] [Homo sapiens]
[Complex:8938885] RUNX1:PML [nucleoplasm] [Homo sapiens]
[Complex:9604705] RUNX1:NOTCH4 gene [nucleoplasm] [Homo sapiens]
[Complex:9616212] CEBPA gene:RUNX1:SPI1:GATA2:TAL1:FLI1:MYB [nucleoplasm] [Homo sapiens]
[Complex:9731008] RUNX1:3b [nucleoplasm] [Homo sapiens]
[Complex:9942724] TBX21:RUNX1 [nucleoplasm] [Homo sapiens]
[Complex:9988694] RUNX1:PHF6 [nucleoplasm] [Homo sapiens]
(hasMember)[DefinedSet:8938850] RUNX1,RUNX1:CBFB [nucleoplasm] [Homo sapiens]
(input)[Reaction:8865320] CBFB binds RUNX1 [Homo sapiens]
[Reaction:8937682] RUNX1 binds SRC [Homo sapiens]
[Reaction:8938867] CCND3,(CCND1,CCND2) binds RUNX1 [Homo sapiens]
[Reaction:8938887] PML binds RUNX1 [Homo sapiens]
[Reaction:9604703] RUNX1 binds NOTCH4 gene [Homo sapiens]
[Reaction:9616214] RUNX1, SPI1 (PU.1), GATA2, TAL1 (SCL), FLI1, and MYB bind the CEBPA promoter [Homo sapiens]
[Reaction:9731051] SARS-CoV-1 3b binds to RUNX1 [Homo sapiens]
[Reaction:9942757] TBX21 binds RUNX1 [Homo sapiens]
[Reaction:9988697] RUNX1 binds PHF6 [Homo sapiens]
(output)[BlackBoxEvent:8935785] RUNX1 mRNA translation is inhibited by miR-17, miR-18a, miR-20a, miR-27a, miR-106a, miR-215, miR-302b, miR-378 and miR-675 [Homo sapiens]
[Reaction:8937767] PTPN11 dephosphorylates RUNX1 [Homo sapiens]
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No pathways have been reviewed or authored by RUNX1 [nucleoplasm] (8865295)