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Details on Person The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes

Class:IdLiteratureReference:8864099
_displayNameThe catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes
_timestamp2016-03-11 19:53:50
author[Person:8864094] Wang, Hong-Mei
[Person:8864098] Xu, Yun-Fei
[Person:8864095] Ning, Shang-Lei
[Person:8864093] Yang, Du-Xiao
[Person:1678952] Li, Y
[Person:8864100] Du, Yu-Jie
[Person:5262925] Yang, Fan
[Person:8864092] Zhang, Ya
[Person:8864113] Liang, Nan
[Person:8864097] Yao, Wei
[Person:8864102] Zhang, Ling-Li
[Person:8864104] Gu, Li-Chuan
[Person:8864108] Gao, Cheng-Jiang
[Person:8864109] Pang, Qi
[Person:8864107] Chen, Yu-Xin
[Person:8864111] Xiao, Kun-Hong
[Person:8864110] Ma, Rong
[Person:8864103] Yu, Xiao
[Person:8864112] Sun, Jin-Peng
created[InstanceEdit:8864114] Orlic-Milacic, Marija, 2016-03-11
journalCell Res.
pages1067-90
pubMedIdentifier25081058
titleThe catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes
volume24
year2014
(literatureReference)[CatalystActivityReference:9644034] protein tyrosine phosphatase activity of Phosphorylated ERBB2:EGFR heterodimers:PTPN18 [plasma membrane] The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes
[Pathway:8863795] Downregulation of ERBB2 signaling [Homo sapiens]
[Reaction:8864105] PTPN18 binds ERBB2:EGFR heterodimers [Homo sapiens]
[Reaction:8864125] PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 [Homo sapiens]
[Complex:8864106] Phosphorylated ERBB2:EGFR heterodimers:PTPN18 [plasma membrane] [Homo sapiens]
[Complex:8864118] Phosphorylated ERBB2(dephosphorylated at Y1196,Y1112 and Y1248):EGFR heterodimers:PTPN18 [plasma membrane] [Homo sapiens]
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