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Details on Person Influx of extracellular calcium

Class:IdBlackBoxEvent:8863009
_displayNameInflux of extracellular calcium
_doReleaseTRUE
_timestamp2016-07-15 23:49:25
authored[InstanceEdit:8862798] Shah, Kavita, 2016-02-23
compartment[Compartment:70101] cytosol
[Compartment:984] extracellular region
created[InstanceEdit:8863015] Orlic-Milacic, Marija, 2016-03-02
disease[Disease:8863054] Alzheimer's disease
edited[InstanceEdit:8870548] Orlic-Milacic, Marija, 2016-05-10
input[SimpleEntity:74112] Ca2+ [extracellular region]
isChimericFALSE
literatureReference[LiteratureReference:8863020] Calcium signals induced by amyloid beta peptide and their consequences in neurons and astrocytes in culture
[LiteratureReference:8862806] Neurotoxicity induces cleavage of p35 to p25 by calpain
modified[InstanceEdit:8863025] Orlic-Milacic, Marija, 2016-03-02
[InstanceEdit:8863056] Orlic-Milacic, Marija, 2016-03-03
[InstanceEdit:8863570] Orlic-Milacic, Marija, 2016-03-08
[InstanceEdit:8863683] Orlic-Milacic, Marija, 2016-03-09
[InstanceEdit:8867562] Orlic-Milacic, Marija, 2016-04-15
[InstanceEdit:8867563] Orlic-Milacic, Marija, 2016-04-15
[InstanceEdit:8870556] Orlic-Milacic, Marija, 2016-05-10
[InstanceEdit:8875080] Orlic-Milacic, Marija, 2016-06-01
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9641190] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameInflux of extracellular calcium
output[SimpleEntity:74016] Ca2+ [cytosol]
regulatedBy[PositiveRegulation:8867561] Positive regulation by 'APP(672-713) [extracellular region]'
regulationReference[RegulationReference:9641359] Positive regulation by 'APP(672-713) [extracellular region]' Calcium signals induced by amyloid beta peptide and their consequences in neurons and astrocytes in culture
releaseDate2016-09-19
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8894759] R-HSA-8863009.4
summation[Summation:8863680] Beta amyloid increases influx of extracellular calcium (Ca2+...
(hasEvent)[Pathway:8862803] Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models [Homo sapiens]
(precedingEvent)[Reaction:8863008] Calpain activation [Homo sapiens]
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No pathways have been reviewed or authored by Influx of extracellular calcium (8863009)