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Details on Person Neurotoxicity induces cleavage of p35 to p25 by calpain

Class:Id	LiteratureReference:8862806
_displayName	Neurotoxicity induces cleavage of p35 to p25 by calpain
_timestamp	2016-03-01 20:21:49
author	[Person:2993961] Lee, M S [Person:8862816] Kwon, Y T [Person:5689956] Li, M [Person:8862809] Peng, J [Person:2672206] Friedlander, R M [Person:6805254] Tsai, L H
created	[InstanceEdit:8862818] Orlic-Milacic, Marija, 2016-03-01
journal	Nature
pages	360-4
pubMedIdentifier	10830966
title	Neurotoxicity induces cleavage of p35 to p25 by calpain
volume	405
year	2000
(literatureReference)	[RegulationReference:9641359] Positive regulation by 'APP(672-713) [extracellular region]' Calcium signals induced by amyloid beta peptide and their consequences in neurons and astrocytes in culture [Summation:8863413] A variety of neurotoxic insults such as beta-amyloid (A-beta... [Pathway:8862803] Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models [Homo sapiens] [Reaction:8863008] Calpain activation [Homo sapiens] [BlackBoxEvent:8863009] Influx of extracellular calcium [Homo sapiens] [Reaction:8863012] Calpain cleaves p35 to p25 [Homo sapiens] [Reaction:8863416] Calpain 1 or Calpain 2 cleaves Cdk5r1 (p35) [Mus musculus] [Complex:8863434] CDK5:p25 [cytosol] [Homo sapiens] [Complex:8863585] CDK5:p25 [nucleoplasm] [Homo sapiens]
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No pathways have been reviewed or authored by Neurotoxicity induces cleavage of p35 to p25 by calpain (8862806)