Query author contributions in Reactome

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Details on Person Edgerton, Mira

Class:Id	Person:8861697
_displayName	Edgerton, Mira
_timestamp	2016-02-20 01:02:27
created	[InstanceEdit:8861701] Shamovsky, Veronica, 2016-02-20
firstname	Mira
initial	M
surname	Edgerton
(author)	[LiteratureReference:8861651] Histatin 5 resistance of Candida glabrata can be reversed by insertion of Candida albicans polyamine transporter-encoding genes DUR3 and DUR31 [LiteratureReference:8861658] Candida albicans Ssa1/2p is the cell envelope binding protein for human salivary histatin 5 [LiteratureReference:8861687] Distinct antifungal mechanisms: beta-defensins require Candida albicans Ssa1 protein, while Trk1p mediates activity of cysteine-free cationic peptides [LiteratureReference:8861690] Candida albicans cell wall ssa proteins bind and facilitate import of salivary histatin 5 required for toxicity [LiteratureReference:8861712] Salivary histatin 5 internalization by translocation, but not endocytosis, is required for fungicidal activity in Candida albicans [LiteratureReference:8861713] Uptake of the antifungal cationic peptide Histatin 5 by Candida albicans Ssa2p requires binding to non-conventional sites within the ATPase domain [LiteratureReference:8861747] Histatin 5 uptake by Candida albicans utilizes polyamine transporters Dur3 and Dur31 proteins [LiteratureReference:8861748] The TRK1 potassium transporter is the critical effector for killing of Candida albicans by the cationic protein, Histatin 5
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No pathways have been reviewed or authored by Edgerton, Mira (8861697)