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Details on Person PP2A demethylation by PPME1

Class:IdReaction:8856951
_displayNamePP2A demethylation by PPME1
_doReleaseTRUE
_timestamp2022-02-08 21:54:32
authored[InstanceEdit:8951416] Jupe, Steve, 2016-12-02
catalystActivity[CatalystActivity:8857795] protein methylesterase activity of PPME1 [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:8856949] Jupe, Steve, 2016-02-12
edited[InstanceEdit:8964092] Jupe, Steve, 2017-02-15
input[Complex:8857787] MeL-PP2A [nucleoplasm] [Homo sapiens]
[SimpleEntity:113518] H2O [nucleoplasm]
isChimericFALSE
literatureReference[LiteratureReference:8856944] Structural mechanism of demethylation and inactivation of protein phosphatase 2A
modified[InstanceEdit:8857796] Jupe, Steve, 2016-02-16
[InstanceEdit:8857835] Jupe, Steve, 2016-02-17
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8964123] Jupe, Steve, 2017-02-15
[InstanceEdit:9764050] Orlic-Milacic, Marija, 2022-02-08
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePP2A demethylation by PPME1
output[Complex:1363265] PP2A [nucleoplasm] [Homo sapiens]
[SimpleEntity:8857797] methanol [nucleoplasm]
precedingEvent
releaseDate2017-03-27
reviewed[InstanceEdit:8964125] Janssens, Veerle, 2017-02-15
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8891657] R-HSA-8856951.3
summation[Summation:8964124] The reversible methylation of the PP2A C subunit is a highly...
(hasEvent)[Pathway:69273] Cyclin A/B1/B2 associated events during G2/M transition [Homo sapiens]
(precedingEvent)[NegativePrecedingEvent:9764042] Futile Cycle: PP2A demethylation by PPME1
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No pathways have been reviewed or authored by PP2A demethylation by PPME1 (8856951)