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Details on Person Tumor necrosis factor receptor superfamily 8 (TNFRSF8, CD30)...
| Class:Id | Summation:8856190 |
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| _displayName | Tumor necrosis factor receptor superfamily 8 (TNFRSF8, CD30)... |
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| _timestamp | 2016-09-16 13:31:53 |
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| created | [InstanceEdit:8856160] Garapati, Phani Vijay, 2016-02-09 |
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| literatureReference | [LiteratureReference:8856146] CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival
[LiteratureReference:8856150] CD30-regulated apoptosis in murine CD8 T cells after cessation of TCR signals
[LiteratureReference:8856166] CD30/CD30 ligand (CD153) interaction regulates CD4+ T cell-mediated graft-versus-host disease
[LiteratureReference:8856176] Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells |
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| modified | [InstanceEdit:8871613] Garapati, Phani Vijay, 2016-05-19
[InstanceEdit:8939161] Jupe, Steve, 2016-09-16 |
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| text | Tumor necrosis factor receptor superfamily 8 (TNFRSF8, CD30) and its ligand TNFSF8 (CD30 ligand, CD30L, CD153) are interacting cell-surface glycoproteins. TNFRSF8 is expressed on activated CD4 and CD8 T cells and B cells. It is a marker for Hodgkin's syndrome. TNFRSF8 signaling regulates hymocyte survival (Blazar et al. 2004) and peripheral T cell responses, controlling T cell survival and down-regulating cytolytic capacity (Duckett et al. 1997, Kurts et al. 1999, Telford et al. 1997). |
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| (summation) | [Reaction:8856189] TNFSF8 binds TNFRSF8 [Homo sapiens]
[Reaction:8856191] Cd30l binds Cd30 [Mus musculus] |
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No pathways have been reviewed or authored by Tumor necrosis factor receptor superfamily 8 (TNFRSF8, CD30)... (8856190)
