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Details on Person PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins

Class:Id	Reaction:8855711
_displayName	PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins
_doRelease	TRUE
_timestamp	2016-05-19 16:46:28
authored	[InstanceEdit:8855708] Jassal, Bijay, 2016-02-05
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:8855708] Jassal, Bijay, 2016-02-05
edited	[InstanceEdit:8855708] Jassal, Bijay, 2016-02-05
input	[Complex:8855701] PALM-C36-ASGR1:PALM-C54,58-ASGR2 [plasma membrane] [Homo sapiens] [SimpleEntity:8855720] proteoglycan [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:8855702] H2, the minor subunit of the human asialoglycoprotein receptor, trafficks intracellularly and forms homo-oligomers, but does not bind asialo-orosomucoid [LiteratureReference:8855709] Nonpalmitoylated human asialoglycoprotein receptors recycle constitutively but are defective in coated pit-mediated endocytosis, dissociation, and delivery of ligand to lysosomes [LiteratureReference:8855878] The H1 and H2 polypeptides associate to form the asialoglycoprotein receptor in human hepatoma cells
modified	[InstanceEdit:8855881] Jassal, Bijay, 2016-02-08 [InstanceEdit:8855974] Jassal, Bijay, 2016-02-08 [InstanceEdit:8862659] Jassal, Bijay, 2016-02-29 [InstanceEdit:8866934] Jassal, Bijay, 2016-04-05 [InstanceEdit:8871616] Weiser, JD [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins
output	[Complex:8855703] PALM-C36-ASGR1:PALM-C54,58-ASGR2:proteoglycan [plasma membrane] [Homo sapiens]
releaseDate	2016-06-15
reviewed	[InstanceEdit:8866933] D'Eustachio, Peter, 2016-04-05
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8873442] R-HSA-8855711.3
summation	[Summation:8855887] Asialoglycoprotein receptors 1 and 2 (ASGR1 and ASGR2) media...
(hasEvent)	[Pathway:446203] Asparagine N-linked glycosylation [Homo sapiens]
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No pathways have been reviewed or authored by PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins (8855711)