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Details on Person FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1

Class:IdReaction:8855237
_displayNameFYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1
_doReleaseTRUE
_timestamp2018-02-24 05:08:19
authored[InstanceEdit:8855238] Jassal, Bijay, 2016-02-03
catalystActivity[CatalystActivity:9038308] protein tyrosine kinase activity of FYN [cytosol]
catalystActivityReference[CatalystActivityReference:9643895] protein tyrosine kinase activity of FYN [cytosol] Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity
compartment[Compartment:70101] cytosol
[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:8855238] Jassal, Bijay, 2016-02-03
edited[InstanceEdit:8855238] Jassal, Bijay, 2016-02-03
input[Complex:8855258] RELN:VLDLR:DAB1:SH3KBP1 [plasma membrane] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:8855233] Hierarchical disabled-1 tyrosine phosphorylation in Src family kinase activation and neurite formation
[LiteratureReference:8855249] Modulation of Reelin signaling by Cyclin-dependent kinase 5
[LiteratureReference:8855224] Reelin-Disabled-1 signaling in neuronal migration: splicing takes the stage
[LiteratureReference:8855246] Dab1-mediated colocalization of multi-adaptor protein CIN85 with Reelin receptors, ApoER2 and VLDLR, in neurons
modified[InstanceEdit:8855254] Jassal, Bijay, 2016-02-03
[InstanceEdit:8862659] Jassal, Bijay, 2016-02-29
[InstanceEdit:8866375] Jassal, Bijay, 2016-03-31
[InstanceEdit:8866932] Jassal, Bijay, 2016-04-05
[InstanceEdit:8866934] Jassal, Bijay, 2016-04-05
[InstanceEdit:8871616] Weiser, JD
[InstanceEdit:9038324] May, Bruce, 2018-02-24
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameFYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1
output[Complex:8855226] RELN:VLDLR:p-Y198,220,232-DAB1:SH3KBP1 [plasma membrane] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2016-06-15
reviewed[InstanceEdit:8866933] D'Eustachio, Peter, 2016-04-05
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8873469] R-HSA-8855237.5
summation[Summation:8855229] One of the three domains in disabled homolog 1 (DAB1) is a t...
(hasEvent)[Pathway:8866376] Reelin signalling pathway [Homo sapiens]
(updatedInstance)[_UpdateTracker:9779795] Update Tracker - [Reaction:8855237] FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 - v64:[add_removeCatalystActivity]
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