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Details on Person VLDLR binds PCSK9

Class:IdReaction:8855111
_displayNameVLDLR binds PCSK9
_doReleaseTRUE
_timestamp2016-05-19 16:46:35
authored[InstanceEdit:8855122] Jassal, Bijay, 2016-02-01
compartment[Compartment:876] plasma membrane
[Compartment:984] extracellular region
created[InstanceEdit:8855122] Jassal, Bijay, 2016-02-01
edited[InstanceEdit:8855122] Jassal, Bijay, 2016-02-01
input[EntityWithAccessionedSequence:6784727] PCSK9 [extracellular region] [Homo sapiens]
[EntityWithAccessionedSequence:5216079] VLDLR [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:8855117] The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2
[LiteratureReference:8866454] Circulating proprotein convertase subtilisin/kexin 9 (PCSK9) regulates VLDLR protein and triglyceride accumulation in visceral adipose tissue
modified[InstanceEdit:8862659] Jassal, Bijay, 2016-02-29
[InstanceEdit:8866451] Jassal, Bijay, 2016-04-01
[InstanceEdit:8866932] Jassal, Bijay, 2016-04-05
[InstanceEdit:8866934] Jassal, Bijay, 2016-04-05
[InstanceEdit:8871616] Weiser, JD
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameVLDLR binds PCSK9
output[Complex:8855118] VLDL:PCSK9 [plasma membrane] [Homo sapiens]
releaseDate2016-06-15
reviewed[InstanceEdit:8866933] D'Eustachio, Peter, 2016-04-05
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8873467] R-HSA-8855111.3
summation[Summation:8855113] Circulating proprotein convertase subtilisin/kexin type 9 (P...
(hasEvent)[Pathway:8866427] VLDLR internalisation and degradation [Homo sapiens]
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No pathways have been reviewed or authored by VLDLR binds PCSK9 (8855111)