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Details on Person UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin

Class:Id	Reaction:8853514
_displayName	UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin
_doRelease	TRUE
_timestamp	2016-08-11 01:23:02
authored	[InstanceEdit:8852253] May, Bruce, 2016-01-14
catalystActivity	[CatalystActivity:8853522] cysteine-type deubiquitinase activity of UCHL3,USP7,USP9X [cytosol]
catalystActivityReference	[CatalystActivityReference:9643105] thiol-dependent ubiquitin-specific protease activity of UCHL3,USP7,USP9X [cytosol] The de novo synthesis of ubiquitin: identification of deubiquitinases acting on ubiquitin precursors
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:8853513] May, Bruce, 2016-01-25
edited	[InstanceEdit:8852253] May, Bruce, 2016-01-14
input	[EntityWithAccessionedSequence:8853517] UBA52(1-128) [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8853528] The de novo synthesis of ubiquitin: identification of deubiquitinases acting on ubiquitin precursors [LiteratureReference:5689593] Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases
modified	[InstanceEdit:8865103] May, Bruce, 2016-03-20 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8933465] May, Bruce, 2016-08-04 [InstanceEdit:8934410] May, Bruce, 2016-08-09 [InstanceEdit:8934572] May, Bruce, 2016-08-11 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin
output	[EntityWithAccessionedSequence:939203] UBA52(1-76) [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:72476] RPL40 [cytosol] [Homo sapiens]
releaseDate	2016-09-19
reviewed	[InstanceEdit:8934570] Azevedo, Jorge E, 2016-08-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8884518] R-HSA-8853514.3
summation	[Summation:8865045] The UBA52 precursor protein contains the ribosomal protein L...
(hasEvent)	[Pathway:8866652] Synthesis of active ubiquitin: roles of E1 and E2 enzymes [Homo sapiens]
(precedingEvent)	[Reaction:8852134] UBA1 adenylates ubiquitin in the cytosol [Homo sapiens] [Reaction:8865090] UBA6 adenylates ubiquitin in the cytosol [Homo sapiens]
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No pathways have been reviewed or authored by UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (8853514)